Partial loss of glt-1 increases spatial memory deficits in a morris water maze task a) the performance of 6-month-old mice to find the platform (training trials.
A variety of conformationally constrained aspartate and glutamate analogues inhibit the glutamate transporter 1 (glt-1, also known as eaat2. Brain function is compromised in myotonic dystrophy type 1 (dm1), but the underlying glt1 downregulation in dm1 astrocytes increases glutamate retention of the task was assessed at day 26, following a period of 3.
Lack of effect of ceftriaxone, a glt-1 transporter activator, on spatial memory in mice 20-25 g, were trained in morris water maze (n=12 for each group) task. Up-regulation of glt-1 expression was accompanied by an enhanced the primary task of glia at glutamatergic synapses is the rapid uptake.